1) Bone Marrow Transplant Pros - the only treatment with a higher potential for cure. Cons - risky procedure, hard to find a donor, can be potentially lethal. 2) Antibiotics Pros - Helpful in children from 2 months to 5 years old to prevent infection like pneumonia. Cons - can promote antibiotic resistance, has side effects 3) Hydroxyurea Pros - reduces frequency of painful attacks and reduces the need for blood tranfusion. Cons - increase infection, may cause leukemia and other tumors 4) Blood Transfusion Pros - increase normal red blood cells, decrease stroke risk Cons- excess iron in the blood